Samphire Neuroscience Reviews 96

TrustScore 4.5 out of 5

4.6

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Review summary

Created with AI, based on recent reviews

Considering 54 reviews, reviewers overwhelmingly had a great experience with this company. Customers consistently praise the product, often describing it as a "game changer" that significantly improves symptoms related to PMDD, PMS, and endometriosis, including mood regulation, pain reduction, and increased clarity. Many users highlight the positive impact on their quality of life, noting a decrease in the need for painkillers and an overall improvement in their daily functioning. The customer service and staff are also frequently commended for being supportive, responsive, and genuinely caring. However, some customers experienced technical issues with the device, such as problems with charging or connectivity, and a few were confused about how the tracked data was being used to provide actionable insights. Additionally, a small number of users did not notice a major improvement in mood regulation, while others found it took multiple attempts to get the device to connect properly.

What people talk about most

Product

Clients share positive opinions on the product, with many describing it as a "game changer" and... See more

User experience

Users describe positive interactions with the user experience. Many reviewers found the device easy to use... See more

Customer service

People report overwhelmingly positive experiences with customer service. Reviewers consistently praise the... See more

Staff

Customers consistently note positive experiences with staff. Reviewers frequently praise the team for being... See more

Quality

Reviewers mention positive feedback about quality. Many customers report a significant improvement in their... See more

Reviews shaping this summary

Rated 5 out of 5 stars

The Nettle has been life changing as someone with pcos and pmdd, and long term depression. It’s helped me to manage my mood and reduced my pain symptoms. It’s not like any other treatment I have exper... See more

Company replied

Rated 5 out of 5 stars

I'm using to see if it improves the symptoms of my recently diagnosed ADHD, which seem to have got much worse now that I am post-menopausal. It's a bit hard to tell but I am finding that I am general... See more

Company replied

Rated 5 out of 5 stars

Less crying, less snapping, just in general a more calm time before my periods. Between loosing weight and pre-menopause, my cycle has become notable longer than it used to be, and I'm so grateful tha... See more

Company replied

Rated 5 out of 5 stars

Using a Nettle has changed my life. The week before my period, are now doable. Before Nettle, I felt overwhelmed, anxious and even angry the week before my period. Now that's replaced with a b... See more

Company replied


Company details

  1. Medical Technology Manufacturer

Written by the company

Samphire Neuroscience is a neurotechnology company dedicated to maximizing the wellbeing of women by delivering pioneering neurotechnology and evidence-based solutions that are drug and hormone-free. Our products include Nettle™, a medically-approved brain stimulation device to tackle PMS and menstrual pain non-invasively, Lutea™, a wellness brain stimulation device to support women during hormonally challenging moments, and the Samphire App, which helps women understand the patterns behind their cycles.


Contact info

4.6

Excellent

TrustScore 4.5 out of 5

96 reviews

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Rated 5 out of 5 stars

Nettle is a revolutionary device for…

Nettle is a revolutionary device for taking back the responsabilitues of our health. It s wonderfull to manage ans schedule a session with nettle the moment u need it.
It is very efficient because we can act daily on our pain and discomfort.

January 9, 2025
Unprompted review
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Reply from Samphire Neuroscience

Thank you so much for sharing your experience!

Rated 5 out of 5 stars

I’ve used nettle for a year now and…

I’ve used nettle for a year now and have noticed a significant difference in my symptoms during my luteal phase. App is easy to use and helpful to track my symptoms !

December 18, 2025
Unprompted review
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Reply from Samphire Neuroscience

Thank you so much for sharing your experience!! You'll also notice an exciting new feature that brings even deeper insights into your symptoms coming out soon 🫶

Rated 5 out of 5 stars

great addition to PMDD treatment

nettle has been such a great addition to my PMDD treatment, truly not much actually works and especially not without side effects. my nettle (while absolutely not 100% effective), takes the edge off to a more manageable level and is really easy to keep up with as part of my routine. also reduces my cramps a bit which I honestly wasn’t expecting at all! i love that this is a women’s team too, our health is so under-researched, and everyone from samphire has been incredibly responsive when I’ve needed it. looking forward to seeing how this continues to develop!

May 17, 2025
Unprompted review
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Reply from Samphire Neuroscience

Thank you so much for sharing your experience! Everyone's response is different, but glad you're able to live a bit easier since integrating Nettle into your routine :)

Rated 5 out of 5 stars

A brilliant product and fantastic customer service,

Fantastic customer service, first of all. I had some questions and immediately got answers from Em. It helped so much as I was overwhelmed at first and was scared to do something wrong, but she went through it all with me and I felt so much more confident using it. I have only recently started using the Nettle regularly (after setting up notifications in the app so it reminds me when I need to use it), so I can’t say just yet how much it’s improving my symptoms of PMDD moods and Endometriosis pain, but after being offered the only treatment option of chemically induced menopause by nhs, and declining that, I’m just so happy to have this device as alternative treatment for these very overlooked and underesearched conditions. I’m very hopeful it will help because there are so many positive reviews and Em is very knowledgeable on these conditions. The device is comfortable and easy to use. Once you’ve used it a few times it becomes second nature to go through the steps. It tingles and itches a bit at first but that only lasts a minute for me and then it’s unnoticeable! I can’t wait to see how this device helps me.

December 15, 2025
Unprompted review
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Reply from Samphire Neuroscience

Thank you so much for sharing your experience - we know too well how heartbreaking it can be to live in pain and yet be offered a single, drastic option. Fingers crossed this is the right solution for you 🫶

Rated 5 out of 5 stars

Nettle is a game changer.

Nettle is a game changer.
I've had it for a year now and it has helped massively with my PMDD. I find it extremely helpful around 10-7 days before my cycle when I feel the most erratic. The feeling when your mind is racing is tuned down almost instantly after using it and I can think in single sentences again.
It helps with endo in reducing the amount of painkillers I take, but I am not really very consistent with it due to my lifestyle/job. I could probably get better results being more consistent.

December 15, 2025
Unprompted review
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Reply from Samphire Neuroscience

Thank you for sharing your experience! Everyone's cycles and symptoms are different, so it's critical to experiment and find what works best for you 🫶 And hectic lives are part and parcel of everyone's every day, so don't be too hard on yourself and try to stay consistent when you can!

Rated 5 out of 5 stars

Using Nettle has been a life saver!

Using Nettle has been a life saver. I use it on days that my symptoms flare, which for me can also be around ovulation. I can feel relief midway through a session sometimes. It has eased cramps and pain, and mostly been incredible for my mood. It has taken the edge off when I’m really spiraling and has brought me back into a regulated state from a very depressed and overwrought place. I have had less suicidal ideation since using it, and when I did feel it, the Nettle device helped bring my thinking back down into a safe place. I’m very thankful and grateful that it exists.

If you are on the fence (like I was because I was a bit worried about messing with my brain) I would highly recommend trying it because it has improved my life and given me a tool. Before I felt alone in dealing with PMDD, even when consulting professionals. I tried therapy, diet changes, birth control, SSRIs, and supplements. Nettle has done more for me than any of the other interventions I’ve tried and in a faster period of time.

Also Samphire seems like a wonderful company. Their customer service is stellar and responsive. They really care about women’s health and want to improve lives. The app is lovely and I now use that to track everything and am getting better data about my cycle and trends.

December 14, 2025
Unprompted review
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Reply from Samphire Neuroscience

🥹🥹🥹 Thank you so much for such a thorough and thoughtful review, and so glad Nettle has been your life saver 🫶

Rated 5 out of 5 stars

Super helpful!

Samphire has been a very supportive company to work with! Any time I've had questions they've responded quickly. And I do think my Nettle does help with my PMDD.

December 13, 2025
Unprompted review
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Reply from Samphire Neuroscience

Thank you for sharing your experience, and we're always here to support!

Rated 5 out of 5 stars

Nettle changed my life

I use Nettle since January and after a few problems I found my rhythm of using and it helps a lot with my symptoms. I also have adhd and I‘m autistic and I have the feeling, that nettle makes me calmer. The best thing of nettle are the people behind it. The Team is so fantastic and passionate.

December 12, 2025
Unprompted review
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Reply from Samphire Neuroscience

Thank you so much for sharing your experience! We see so many people with overlapping conditions like yours, and so glad it has been helpful for you so far 🫶

Rated 5 out of 5 stars

Nettle has been such a welcome addition…

Nettle has been such a welcome addition to my PMDD treatment. I love that this has been designed and made by women, for people who are often forgotten by our patriarchal medical systems. Firstly, the team go above and beyond – the care and support is next level, it’s personalised, it’s prompt and I trust the team want the best for me. I do multiple things to manage my PMDD, so it’s hard to pin down the effect of individual treatments, however I can say this has definitely helped raise the floor and level out the extreme drops. Sometimes when I’m having good month and use Nettle anyway, I feel more energised and alert. It’s also a good comfort-blanket to know I have something science-backed and non-invasive whenever I need it. I love that the app gets updated from us, the community. I’ve had a couple of suggestions implemented and that feels wonderful to be part of! No big-pharma or tech-bros over here. Love your work team ❤️

March 10, 2025
Unprompted review
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Reply from Samphire Neuroscience

Thank you so much for the kind words 🫶 And 100% every person will end up with a different set of solutions - we're all different! And we're here always to help you troubleshoot what works best for you and how neurotechnology can be part of (or the full!) solution for you.

Rated 3 out of 5 stars

My experience wasn't smooth from the…

My experience wasn't smooth from the beginning. I wasn't able to connect Nettle with my personal smartphone. It only worked with other smartphone. And the app itself acts very strange, one time all texts and images/videos are visible, other time no images/videos visible and even text on buttons are not fully visible, it is happening when trying to run session with instruction step by step. Also resently Nettle starts not turning on even it was charged over the night. And I was needed to recharge it again. And next day it is happening again I need to recharge to be able start a session.
I still have hope that it will help me. It is only two cycles of period past, so I can't say if it is really helping. Maybe the mood is better. But still no affection to pain strenght.

December 11, 2025
Unprompted review
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Reply from Samphire Neuroscience

Thank you so much for sharing your experience! As long as you're using the latest software on your smartphone, this shouldn't be an issue, but we're always happy to troubleshoot with you one-on-one over message or call at support@samphireneuro.com. Most people start seeing best effects around month 3 and onwards, so fingers crossed it keeps getting better and giving you the relief you deserve.

Rated 5 out of 5 stars

Total lifesaver!

I suffer from PMDD and Nettle has been a lifesaver for me! For 2 weeks of every month I used to suffer from extreme anxiety and depression that was debilitating. Since using Nettle my symptoms are so much more manageable. It’s really helped me when I felt I was running out of options. Also, the team that run it are amazing people, they are always there to answer any questions you may have and you can tell they really care! Cannot recommend this product enough!

December 11, 2025
Unprompted review
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Reply from Samphire Neuroscience

🥹 thank you for sharing your experience!

Rated 5 out of 5 stars

5***** for PMDD & for women in general

Since joining Samphire and getting the Nettle headband, my life has changed so much. I suffer with PMDD and my periods can vary however since using Nettle, I have seen a significant decrease in physical and mental symptoms and it’s not half as bad as what it’ll my symptoms could be. I’m still quite new to nettle but I honestly won’t ever go without it. Thank you so much to the team at Samphire.

December 11, 2025
Unprompted review
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Reply from Samphire Neuroscience

Thank YOU for giving Nettle a try 🫶

Rated 5 out of 5 stars

Life changing

Nettle has completely transformed my life. My PMDD symptoms are significantly reduced and whilst not completely gone, what felt like drowning in a storm now feels like navigating it in a pretty sturdy ship.

I feel like I have more control over my symptoms, I’m able to do more of the things that I do outside of luteal phase, and I have more mental clarity. Instead of my cycle feeling like two opposite ends of the spectrum, it now feels more balanced and less like I have to spend the first week of my cycle recovering from luteal the week before.

Thank you so much Samphire Neuroscience. I discovered Nettle through a Queen Mary University trial and I hope one day for all people who experienced PMDD that it will be available on the NHS. It truly has changed my life

December 11, 2025
Unprompted review
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Reply from Samphire Neuroscience

Thank you so much for sharing your experience! We are working very hard to have our neurotechnology integrated as part of healthcare pathways, and will continue persevering to make it available on the NHS 💪 In the meantime, we'll continue offering a 3-month returns policy to allow everyone to try Nettle or Lutea risk-free!

Rated 5 out of 5 stars

Excellent Product & Outstanding Customer Care

Samphire is a startup exactly as it should be: delivering an innovative and truly needed product in the way customers actually need it. They stay close, listen carefully to feedback and respond quickly whenever improvements are required.
I’m very satisfied with both the product and the service — highly recommended!

December 11, 2025
Unprompted review
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Reply from Samphire Neuroscience

We're working hard every day to bring our best - women should have had it long ago 🙈

Rated 5 out of 5 stars

Absolutely life changing device

Absolutely life changing device. I have seen such a difference in my symptoms since using this. Less pain, fewer mental health concerns. Customer service has been impeccable.

December 11, 2025
Unprompted review
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Reply from Samphire Neuroscience

Changing your life is what we're here for!!

Rated 5 out of 5 stars

Life changing for PMDD

I have now been using Nettle for over a year and it is life changing.
PMDD symptoms are vastly reduced.
It is very easy to use, I have very thick hair and it hasn’t been an issue.
Customer service are very responsive and were very helpful when I had charging issues.

December 11, 2025
Unprompted review
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Reply from Samphire Neuroscience

Thank you for sharing your experience, especially around how easy it is to use Nettle, Hope! 🫶

Rated 4 out of 5 stars

Early buyers update

I’m one of the early buyers of the Nettle neurostimulation headband in France, and I’ve been using it since the very beginning. I can honestly say it has completely changed the way I experience my period.

I used to have extremely painful periods — the kind that forced me to take painkillers every single month since my very first cycle. I’m 30 now, and since I started using Nettle, I haven’t taken a single painkiller. For me, that alone is absolutely huge. Some months my pain goes down to almost zero, and even on the more difficult ones, it’s still nothing compared to what I used to go through.

For mood regulation, I didn’t notice a major improvement. However, knowing that my pain will be low or manageable has removed a lot of the fear and anxiety I used to feel before my cycle. That in itself has made the whole experience emotionally easier.

I also noticed that my period flow has become much lighter — I can’t say for sure if this is related to Nettle, but it has been consistent since I started using it.

I have experienced ongoing technical issues with the device and had to send it back multiple times. But the Samphire team has always been incredibly responsive and helpful. They answered quickly, guided me through the process, and always found a solution. Their customer service really stands out.

Even with the technical problems, I genuinely believe this headband has drastically changed my life, and I truly wish it could be known and accessible to every woman who struggles with period pain.

December 11, 2025
Unprompted review
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Reply from Samphire Neuroscience

Thank you so much for your review and apologies for the inconvenience needing to get replacements for your device! We have strong warranty policies and want to make sure everyone has the best experience they can with Nettle, so appreciate you persevering and reaping the benefits 🌟

Rated 5 out of 5 stars

Most incredible decision I have made to…

Most incredible decision I have made to support my health. My pain is much more manageable, my quality of life has improved drastically. Also, the customer support is out of this world. I recommend this to everyone I believe it could be useful for. Incredible 100/10!

December 2, 2025
Unprompted review
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Reply from Samphire Neuroscience

Thank you so much for sharing your experience, Shan!

Rated 5 out of 5 stars

Using a Nettle has changed my life

Using a Nettle has changed my life. The week before my period, are now doable.

Before Nettle, I felt overwhelmed, anxious and even angry the week before my period. Now that's replaced with a bit of tiredness and most importantly my happiness stays throughout my cycle.

This headband is an absolute game changer!! I am literally recommending it to any woman, who deals with an overwhelming luteal phase.

Thank you so much Samphire Neuroscience, everyone I have been in contact with has been so helpful and kind.

November 13, 2025
Unprompted review
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Reply from Samphire Neuroscience

!!! So amazing to hear! Thank you for sharing 🫶

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